Archive for the ‘Chinese Herbs in the news’ Category

Report that Chinese Herbs Help Cure Cancer

Thursday, August 19th, 2010

Chinese herbs are good for what ails you! I came across this study review on Huang Qin Tang. I myself have only taken Huang Qin Tang once and for only a short time during a particularly nasty GI virus. I won’t lie to you- the taste is not for the faint of heart. But I am guessing if you are trying to treat colon cancer like the mice in this study,

Go Gravity!

Tuesday, July 13th, 2010

Gravity: Just a Theory

As moderator of this blog, I get the privilege of sorting through real comments versus spam comments. The spam filter mostly does a great job, but periodically a few slip through. Usually I can tell immediately what is spam versus what is real because the authors of spam typically link to websites offering me a hot long night with my new laptop so I can work at home and make $12K a month in real estate. But this post comment has me confused enough that I let it through. Specifically, it says,

“Chinese herbs do work because it is time tested.”

If I was a betting women, and those of you who have played poker with me know I am, I would bet this is actually spam. The tells on this comment are:

  • It’s a really old blog post and anyone who actually cared to comment did so a long while ago
  • It contains a really basic grammar mistake that most native English speakers wouldn’t make
  • As comments go, it’s just plain stupid.

So at the risk of offending Alexa Stewart, you’re wrong.

However, Alexa brings to my attention something that I hear more often than I would like, this notion that Chinese herbs “work because they are time tested.” (I’m sorry, I just could not leave that subject-verb agreement mistake alone).

This brings me to Isaac Newton. I know, it’s a jump, but hang in there with me. (more…)

Red, Red Wine….

Tuesday, June 22nd, 2010

Oh precious, I have you in my sights

Imagine my pleasure when I came across this article reporting that scientists have determined the mechanism by which the polyphenols in red wine inhibit cancer cell growth. Hooray for red wine! But wait, there’s a catch. Dr Gerald Weissmann, MD is quoted in the article:

“As long as they are taken in moderation, all signs show that red wine and green tea may be ranked among the most potent ‘health foods’ we know.”

There’s that sticky word, moderation.

It reminds of a time, just after college when my best friend and I took a celebratory trip to Spain. We toured around, saw sights, ate the food and drank the wine. One particularly hot and sunny day, we spent the afternoon in the sun on the beach. That night we met up with some other Americans for dinner, and started drinking red wine. After dinner, it hardly seemed fashionable to end the party, so we drank some more wine. In particular, we drank just about the cheapest Spanish rioja available. It was so cheap that $5 bought the bottle, the guy uncorked it, and then handed us 4 waxed paper cups to drink it out of. (more…)

Lead, Mercury, Cadmium & Arsenic- Oh My!

Thursday, May 27th, 2010
An actual case of heavy metal contamination

An actual case of heavy metal contamination

When my husband and I got married 5 years ago, many people had their doubts whether we would make it for two fundemental differences in our beliefs

  • he’s a Yankee’s fan- hello, Red Sox fan here!
  • he’s card-carrying, small-government, fiscal-restraint Republican- and I just wasn’t

But as time passes, and once respectable media outlets like the New York Times continue to run sensationalist crap, I find I am being pulled into the right wing conspiracy.

Specifically, this latest article reported the recent findings of a GAO report on dietary supplements.The first paragraph of the article reads:

Nearly all of the herbal dietary supplements tested in a Congressional investigation contained trace amounts of lead and other contaminants, and some supplement sellers made illegal claims that their products can cure cancer and other diseases, investigators found.

Anyone who bothers to continue reading will find in the second paragraph that those tested supplements that contained lead in fact “did not exceed thresholds considered dangerous”. But really, how many readers get to the second paragraph? (more…)

Diving Back into the Swamp!

Monday, April 12th, 2010
Are there gators in there?

Are there gators in there?

This article reviews a survey of physicians, most of whom are in the UK, about their perception of their own understanding and attitudes about herbs. Try not to be too shocked here, but generally, they don’t like herbs, they don’t know anything about herbs, and most of all, they don’t want their patients taking herbs. To be fair, I added the emphasis on that last bit. But in looking at the underlying survey results, it’s not terribly inaccurate. (more…)

Am I pharmacovigilante?

Wednesday, March 17th, 2010
I came across this Candian study http://www.biomedcentral.com/1472-6882/10/8 wherin the
researchers interviewed people who had self reported adverse reactions to natural health
products (NHP), which included
“…vitamins (regardless of source), minerals, traditional Chinese medicines,
Ayurvedic medicines, Native North American medicines, traditional herbal remedies and
homeopathic medicines.”
Specifically, the researchers wanted to understand, when people had an adverse reaction to
NHPs, who did they tell? The answers varied, but had a common theme: not their doctors. As
to why they didn’t tell their doctors, perhaps the best summary was delivered by study
participant identified as Consumer 4:
“I’ve had a doctor tell me that I [the doctor] don’t really believe in all that [NHP]
stuff. So I personally wouldn’t bother telling them about my adverse effects. I’d
just tell the naturopath, or the health food store. (Consumer 4)”
The researchers, in my opinion, correctly highlighted:
“A key finding was that the relationship between consumers and their service
providers can act as a barrier or facilitator to reporting of suspected ADRs. Other
research suggests that participants perceive high quality healthcare to include
recognition of their status as informed patients and acknowledgement of their personal
worth. In the present study, participants felt that their physicians or pharmacists would
ignore their concerns or question their values and beliefs in NHPs. This type of response
negatively impacts the participants’ abilities to maintain open and honest relationships
with their healthcare providers.”
Since the goal of all this interviewing was ultimately to improve reporting of adverse reactions to Health Canada, who in turn aggregates that information in an easily accessable format, the researchers go on to suggest a solution. They suggest that
other people, non-doctos, including health food store workers and NHP manufacturers should be held accountable for reporting.
Stunningly, the researchers seem to have completely missed what I think would be a much
simpler solution. Instead of trying to educate a whole new population on how to navigate the complex beuracracy of reporting to Health Canada, why not re-educate the people who already understand it, the doctors, how to compasionately listen to their patients?  Why not encourage the doctors to become the sort of confidants that people want to talk to about their adverse reactions to NHPs.
http://www.biomedcentral.com/content/pdf/1472-6882-10-8.pdf
Does talking to your doctor feel like this?

Does talking to your doctor feel like this?

I came across this Candian study, Consumers of natural health products: natural-born pharmacovigilantes? wherin the researchers interviewed people who had self reported adverse reactions to natural health products (NHP), which included ”…vitamins (regardless of source), minerals, traditional Chinese medicines, Ayurvedic medicines, Native North American medicines, traditional herbal remedies and homeopathic medicines.” Specifically, the researchers wanted to understand, when people had an adverse reaction to NHPs, who did they tell?

The answers varied, but had a common theme: not their doctors. (more…)

Trolling for news

Monday, March 15th, 2010

Increasingly,traditional Chinese herbs are showing up in the news.  Sometimes good, sometimes bad, often times misrepresented. My request to all of you, if you see an article, or news report, or blog post, or even a really interesting looking advertisement about Chinese herbs, send me the link.  Chances are pretty good that I am going to have a correction to make or additional information to add, or, at the very least, an opinion. And that all belongs here! There are plenty of avenues to send links to me, but the most direct is to email me: jeanine@herbalogic.net

Always…. Never…. What’s a consumer to do?

Tuesday, March 2nd, 2010
This British article was brought to my attention this morning. Once again, sensationalism sells- if you read the article, you’ll notice that it has painfully little to do with the headline. In fact, upon reading the headline, I was all set to start bashing the article as once again being irresponsible journalism. But upon reading the whole thing, I find that I agree with some of what is said, though not all of it.
Not terribly unlike the way we do things in Texas, in the UK, there is the Association of Traditional Chinese Medicine (UK) that sets the standards for practitioners of acupuncture and Chinese herbal medicine. In the US, the NCCAOM fills this role. And from what I can tell, in the UK to be an acupuncturist, you have to meet the ATCM requirements. Here in the US, the role of deciding who can practice acupuncture is left to individual states, but many of them, including Texas, rely heavily on the NCCAOM in that the states require individuals wishing to obtain an acupuncture license to pass the NCCAOM standardized tests.
And then it seems there is a loophole, both in Texas and the UK. There is no specific license to be just a Chinese herbalist who does not practice acupuncture. This can potentially lead to people who don’t know what they are doing making people sick.
In the UK, some people claim the solution is more regulation. I have heard this argument in the US as well. But as my graduate epidemiology professor once said with regard to the suggestion that the US federal government should take a greater role, “Really? You want the folks who brought us FEMA to be in charge of that?”
I have another suggestion- let’s treat people like the responsible adults that they are, educate them, and let them make their own decisions.
Here’s my first contribution to that educational effort, and I call it the unique distinction that comes with the words ALWAYS and NEVER. If someone tells you that Chinese herbs are ALWAYS safe, because they come from plants, he does not know what he is talking about. And if someone tells you that you should NEVER use Chinese herbs, because they are unregulated and contain drugs, he does not know what he is talking about.
Are Chinese herbs sometimes unsafe- yes. That’s why I went to school for 4 years and get continuing education every year in order to use them safely and effectively. And more importantly, I know when I am out of my depth and refer people to other, more experienced practitioners. Even in the case of the much talked about herbs containing aristolochic acid, traditional and modern texts all caution the use of these herbs to be short term and not for use in people with damaged or susceptible yin (that’s traditional speak for kidney problems).
Do Chinese herbal preparations sometimes contain other things they shouldn’t, i.e. contaminants, put there intentionally by the manufacturer or through negligence- yes. And that is why as a consumer you should buy products from reputable sources, made by people who can answer your questions clearly. Consumers should learn how to discern which herbs are safe, common and helpful, and which should be avoided.
To make an analogy, consumers can walk into any vitamin isle at their local pharmacy and buy Vitamin A. Vitamin A is an essential part of a healthy diet, and is known to associate with the proper functioning of vision, the immune system, preventing cancer and the healthy turnover of epithelial cells. But when consumed by an adult in an excess of 25,000 IU daily, vitamin A can cause tiredness, discomfort, lethargy, upset stomach, decreased appetite, vomiting, joint soreness, irritability, headache, drying and cracking of the lips and skin, hair loss, and yellowing of the skin. In pregnant women, an excess of vitamin A can cause birth defects in the fetus.

This British article was brought to my attention this morning. Once again, sensationalism sells- if you read the article, you’ll notice that it has painfully little to do with the headline. In fact, upon reading the headline, I was all set to start bashing the article as once again being irresponsible journalism. But upon reading the whole thing, I find that I agree with some of what is said, though not all of it. (more…)

Viagra, Cealis, and Horny Goat Weed

Thursday, February 18th, 2010

My husband sent me a link to this science blog with a review on a patent dispute between Pfizer, makers of Viagra, and Eli Lilly & Co., makers of Cialis. And though I am not entirely clear on the legal details, somehow the Chinese herb, Yin Yang Huo, aka Horny Goat Weed, has entered into the patent dispute.

But what I particularly want to highlight about this author’s review of Viagra versus Yin Yang Huo is his comment:

“Horny goat weed extract must be used at unbelievably high concentrations – far more than can be achieved in the bloodstream – to cause only 1/10th the effectiveness of sildenafil  [active ingredient in Viagra] in a rabbit penile blood vessel model.”

And I would like to suggest that maybe that’s not a bad thing. (more…)

Chinese Herb in Cancer Study Already Banned in U.S.

Wednesday, December 23rd, 2009
Saying Chinese Herbs Cause Cancer Equals Bad Science
Recently the article Alternative Medicine Warning: Some Chinese Herbs May Increase Cancer Risk came to my attention.  The Fox News report reviews an academic article published by the Journal of the National Cancer Institute. Having more than a passing interest in Chinese herbal medicine, I chased down the original article, Population-Based Case-Control Study of Chinese Herbal Products Containing Aristolochic Acid and Urinary Tract Cancer Risk (Lai, Wang, et. all).  The authors concluded, “Consumption of aristolochic acid–containing Chinese herbal products [mu tong] is associated with an increased risk of cancer of the urinary tract in a dose-dependent manner that is independent of arsenic exposure.”
A long time student of mathematics and a more recent student of public health and biostatistics, I set about critically analyzing this paper.  I have two observations that cause me to personally call to question the validity of the authors’ conclusion.
Which herb are we talking about?
In traditional Chinese herbal medicine, there are two different herbs that are colloquially referred to as mu tong. Guan mu tong, or aristolochia, contains aristolochic acid, a known nephrotoxin. In modern practice, this herb is rarely used and is banned from importation to the United States by the Food & Drug Administration (FDA).  Chuan mu tong, or caulis mutong, on the other hand is not known to contain aristolochic acid. Chuan mu tong is effectively used to treat urinary tract infections and promote lactation in cases of blocked milk ducts.
The authors of the study make no distinction in their report if they are reviewing cases of people using chuan mu tong or guan mu tong, though considering their interest in aristolochic acid, I would guess they are studying the potentially carcinogenic effects of guan mu tong. Considering that guan mu tong is neither legal nor widely available for use, I question why Fox news took such an interest in this publication initially.
Confounding variables
In stastical analysis, a confounding variable is something that relates to both the dependent and independent variable. Study methodologies need to control for confounding variables in order to avoid making invalid inferences about the relationship of the variables being studied.
For example, suppose a study wants to determine if performing regular weight-bearing exercise is an effective way to prevent osteoporosis in post-menopausal women. Women are selected for the study and categorized as either doing the exercise or not. But suppose also that the women in the weight-bearing exercise also regularly take a calcium supplement, which is known to prevent osteoporosis. Without taking this fact into consideration and making appropriate statistical adjustments, analysis might incorrectly conclude that the weight-bearing exercise had a greater role in preventing osteoporosis than it actually did.
In the study concerning mu tong, the authors considered and accommodated for the presence of significant levels of arsenic in the subjects’ drinking water (arsenic is known to cause urinary tract cancer). However, the authors site in their limitations section that smoking status was not considered during analysis. Personally, I have reviewed many articles regarding cancer and possible causative agents and I cannot think of one that was considered authoritative in which smoking tobacco products, a well established carcinogenic habit, was not considered and controlled for.
Personally, I am appalled to think that a combination of poorly designed scientific research and irresponsible journalism could lead people to the conclusion that Chinese herbs cause cancer.
Jeanine Adinaro is a licensed acupuncturist (Texas) and CEO of Third Coast Herb Company, Inc., a Texas company specializing in quality controlled Chinese herbal remedies, and manufacturer of Herbalogic concentrated herb drops. She also holds an MS degree in theoretical mathematics and has done graduate work in public health at the University of Texas.

Recently the article Alternative Medicine Warning: Some Chinese Herbs May Increase Cancer Risk came to my attention.  The Fox News report reviews an academic article published by the Journal of the National Cancer Institute. Having more than a passing interest in Chinese herbal medicine, I chased down the original article, Population-Based Case-Control Study of Chinese Herbal Products Containing Aristolochic Acid and Urinary Tract Cancer Risk (Lai, Wang, et. all).  The authors concluded, “Consumption of aristolochic acid–containing Chinese herbal products [mu tong] is associated with an increased risk of cancer of the urinary tract in a dose-dependent manner that is independent of arsenic exposure.”

A long time student of mathematics and a more recent student of public health and biostatistics, I set about critically analyzing this paper.  I have two observations that cause me to personally call to question the validity of the authors’ conclusion.

Which herb are we talking about?

In traditional Chinese herbal medicine, there are two different herbs that are colloquially referred to as mu tong. Guan mu tong, or aristolochia, contains aristolochic acid, a known nephrotoxin. In modern practice, this herb is rarely used and is banned from importation to the United States by the Food & Drug Administration (FDA).  Chuan mu tong, or caulis mutong, on the other hand is not known to contain aristolochic acid. Chuan mu tong is effectively used to treat urinary tract infections and promote lactation in cases of blocked milk ducts.

The authors of the study make no distinction in their report if they are reviewing cases of people using chuan mu tong or guan mu tong, though considering their interest in aristolochic acid, I would guess they are studying the potentially carcinogenic effects of guan mu tong. Considering that guan mu tong is neither legal nor widely available for use, I question why Fox news took such an interest in this publication initially.

Confounding variables

In stastical analysis, a confounding variable is something that relates to both the dependent and independent variable. Study methodologies need to control for confounding variables in order to avoid making invalid inferences about the relationship of the variables being studied.

For example, suppose a study wants to determine if performing regular weight-bearing exercise is an effective way to prevent osteoporosis in post-menopausal women. Women are selected for the study and categorized as either doing the exercise or not. But suppose also that the women in the weight-bearing exercise also regularly take a calcium supplement, which is known to prevent osteoporosis. Without taking this fact into consideration and making appropriate statistical adjustments, analysis might incorrectly conclude that the weight-bearing exercise had a greater role in preventing osteoporosis than it actually did.

In the study concerning mu tong, the authors considered and accommodated for the presence of significant levels of arsenic in the subjects’ drinking water (arsenic is known to cause urinary tract cancer). However, the authors site in their limitations section that smoking status was not considered during analysis. Personally, I have reviewed many articles regarding cancer and possible causative agents and I cannot think of one that was considered authoritative in which smoking tobacco products, a well established carcinogenic habit, was not considered and controlled for.

Personally, I am appalled to think that a combination of poorly designed scientific research and irresponsible journalism could lead people to the conclusion that Chinese herbs cause cancer.